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2021 High quality Nicotinamide Adenine - Esterase&Lipase (PLE&CALB) – SyncoZymes

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2021 High quality Nicotinamide Adenine - Esterase&Lipase (PLE&CALB) – SyncoZymes Detail:

There are 26 kinds of PLE enzyme products (Number as ES-PLE-101~ES-PLE-126) developed by SyncoZymes. ES-PLE can be used for the hydrolysis of aliphatic and ester compounds, or regioselective and stereoselective resolution to synthesize chiral acids and their derivatives.

Catalytic reaction type:

Esterase&Lipase (PLE&CALB)
Esterase&Lipase (PLE&CALB)1

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Normally, the reaction system should include substrate, buffer solution and the ES-PLE. The esterification of some ES-PLEs is carried out in the organic phase.
➢ All kinds of ES-PLEs corresponding to various optimum reaction conditions should be studied individually.

Example 1(Biosynthesis of Pregabalin Intermediate) (1):

calb1

Example 2 (2):

calb2

Example 3 (3):

calb3

Example 4(4):

calb5

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH.

1. Xu FX, Chen SY, Xu G, e tal. Appl. Biotechnol Bioproc E, 1988, 54(4): 1030.
2. Huang, F.C., Lee, L. F., Mittal, R. S. D. e tal. J. Am. Chem.Soc, 1975, 97, 4144.
3. Kielbasinski, P., Goralczyk, P., Mikolajczyk, M., e tal. Synlett, 1994, 127.
4. Gais, H. J., Griebel, C., Buschmann, H. Tetrahedron:Asymmetry 2000, 11, 917


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2021 High quality Nicotinamide Adenine - Esterase&Lipase (PLE&CALB)  – SyncoZymes detail pictures

2021 High quality Nicotinamide Adenine - Esterase&Lipase (PLE&CALB)  – SyncoZymes detail pictures


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We're convinced that with joint endeavours, the business between us will bring us mutual benefits. We are able to guarantee you products high quality and competitive value for 2021 High quality Nicotinamide Adenine - Esterase&Lipase (PLE&CALB) – SyncoZymes , The product will supply to all over the world, such as: Tunisia, kazakhstan, Senegal, We are committed to meet all your needs and solve any technical problems you may encounter with your industrial components. Our exceptional products and vast knowledge of technology makes us the preferred choice for our customers.
  • Superb technology, perfect after-sales service and efficient work efficiency, we think this is our best choice.
    5 Stars By Laura from Curacao - 2018.06.09 12:42
    We feel easy to cooperate with this company, the supplier is very responsible, thanks.There will be more in-depth cooperation.
    5 Stars By Jodie from belarus - 2017.04.18 16:45
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