2021 New Style Nadp+ And Nadph - Amine Dehydrogenase (AmDH) – SyncoZymes

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2021 New Style Nadp+ And Nadph - Amine Dehydrogenase (AmDH) – SyncoZymes Detail:

AmDH

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme and coenzyme regeneration system (e.g. glucose and glucose dehydrogenase).
➢ AmDH should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.

Example 1(Synthesis of corresponding chiral amines by reductive amination of alkyl aryl ketones)⁽¹⁾:

AmDH1

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.

1. Kong W, Liu Y, Huang C, et al. Angewandte Chemie International Edition, 2022: e202202264.

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