SyncoZymes

products

Big Discount Nadh 5mg - Transaminase (ATA) – SyncoZymes

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Generally customer-oriented, and it's our ultimate goal for being not only the most trusted, trustable and honest provider, but also the partner for our customers for Nicotinamide Riboside Powder , Best Nicotinamide Mononucleotide Supplement , Cdmo Full Form In Pharma , Our products have exported to North America, Europe, Japan, Korea, Australia, New Zealand, Russia and other countries. Looking forward to build up a good and long term cooperation with you in coming future!
Big Discount Nadh 5mg - Transaminase (ATA) – SyncoZymes Detail:

Enzymes: Are macromolecular biological catalysts, most enzymes are proteins.

Transaminases: A class of enzymes that catalyze amino transferring between amino acids and keto acids. Transaminases are key biological enzymes in asymmetric synthesis and racemic resolution of chiral amines.
Aminotransferase can be divided into four classes according to sequence and structure: Ⅰ, Ⅱ, Ⅲ and Ⅳ. ω-aminotransferases belong to class II transaminases, commonly be used in the preparation of chiral amines and unnatural amino acids, such as β-amino acids.

ω-aminotransferases: In most cases, ω-transaminase refers to a class of enzymes, that catalytic ammonia transfer reactions without α-amino acid as substrate or product.

Catalytic mechanism:

Transaminase ATA1

Enzymes Product Code Product Code
Enzyme Powder ES-ATA-101~ ES-ATA-165 a set of 65 ω-Transaminases, 50 mg each 65 items * 50mg / item, or other quantity
Screening Kit (SynKit) ES-ATA-6500 a set of 65 ω-Transaminases, 1 mg each 65 items * 1mg / item

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion efficiency.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Enzyme screening should be carried out for specific substrates because of the substrate specificity, and get an enzyme that catalyzes the target substrate with best catalytic effect.
➢ Never contact with extreme conditions such as: high temperature, high/low pH and organic solvent with high concentration.
➢ Normally, the reaction system should include substrate, buffer solution, amino donor (such as amino acids and 1-phenyl ethylamine) or receptor (such as keto acids), coenzyme (PLP), cosolvent (such as DMSO).
➢ ATA should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.
➢ All kinds of ATA have various optimum reaction conditions, so each of them should be further studied individually.

Example 1(synthesis of Sitagliptin, asymmetric synthesis) (1):

Transaminase ATA2

Example 2 (Mexiletine, Combination of kinetic resolution with asymmetric synthesis)(2):

Transaminase ATA3

1 Savile CK, Janey JM, Mundorff EC, et al. Science, 2010, 329(16), 305-309.
2 Koszelewski D, Pressnitz D, Clay D, et al. Organic letters, 2009,11(21):4810-4812.


Product detail pictures:

Big Discount Nadh 5mg - Transaminase (ATA)  – SyncoZymes detail pictures


Related Product Guide:

Our firm sticks to the basic principle of "Quality is the life of your company, and status will be the soul of it" for Big Discount Nadh 5mg - Transaminase (ATA) – SyncoZymes , The product will supply to all over the world, such as: Mauritania, Vancouver, Guyana, Our expert engineering team will generally be prepared to serve you for consultation and feedback. We're able to also give you with free of charge samples to meet your requirements. Best efforts will likely be produced to provide you the best service and merchandise. When you are keen on our business and items, make sure you speak to us by sending us emails or call us quickly. In an effort to know our merchandise and company extra, you may come to our factory to view it. We'll generally welcome guests from all over the world to our business to create business relations with us. Be sure to feel cost-free to speak to us for small business and we believe we are going to share the best trading experience with all our merchants.
  • The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
    5 Stars By Natalie from Jakarta - 2017.01.28 19:59
    Hope that the company could stick to the enterprise spirit of "Quality, Efficiency, Innovation and Integrity", it will be better and better in the future.
    5 Stars By Hazel from Australia - 2017.03.28 12:22
    Write your message here and send it to us