SyncoZymes

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Cyclooxygenase (COX)

Short Description:

About Cyclooxygenase

ES-COX (Cyclooxygenase): catalyzes the conversion of C=C bonds to epoxide. There are 11 kinds of COX enzyme products (Number as ES-COX101~ ES-COX-111) developed by SyncoZymes. According to different catalytic mechanism, the COX of SyncoZymes is divided into haloperoxidase and styrene monooxygenase. ES-COX101, 102, 107-111 belong to haloperoxidase, while ES-COX103-106 belong to styrene monooxygenase.

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E-Mail: lchen@syncozymes.com


Product Detail

Product Tags

About Cyclooxygenase:

Catalytic reaction type:

Haloperoxidase:

Cyclooxygenase COX2

Styrene monooxygenase:

Cyclooxygenase COX3

Product Information:

Cyclooxygenase COX
Enzymes Product Code Specification
Enzyme Powder ES-COX-101~ ES-COX-110 a set of 10 NADH Cyclooxygenase, 50 mg each 10 items * 50mg / item, or other quantity

Advantages:

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

Instructions for use:

➢ Normally, haloperoxidase reaction system includes: substrate, buffer, enzyme, H2O2 and halogen ion. Styrene monooxygenase reaction system includes substrate, buffer, enzyme, coenzyme and coenzyme regeneration system
➢ COX should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.

Application Examples:

Example 1(Synthesis of epoxy styrene derivatives from styrene derivatives)(1):

Cyclooxygenase COX4

Note: application examples and references are intended to indicate the application scope of COX for ease of understanding, and do not correspond to the specific enzyme of SyncoZymes.

Storage:

Keep 2 years below -20℃.

Attention:

Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.

References:

1. Lin, Hui, Yan Liu, and Zhong-Liu Wu. Tetrahedron: Asymmetry 22.2 (2011): 134-137.


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