D-Amino acid dehydrogenase (D-AADH)
Short Description:
About D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): an enzyme that can reduce 2-keto acid into corresponding D-amino acid. The reaction need NADP(H) and inorganic ammonia donor (such as ammonia or ammonium ion). There are 17 kinds of D-amino acid dehydrogenases (Number as ES-DAADH-101~ ES-DAADH-117) developed by SyncoZymes.
Catalytic reaction type:
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| Enzymes | Product Code | Specification |
| Enzyme Powder | ES-D-AADH-101~ ES-D-AADH-117 | a set of 17 D-amino Acid Dehydrogenases, 50 mg each 17 items * 50mg / item, or other quantity |
| Screening Kit (SynKit) | ES-D-AADH-1700 | a set of 17 D-amino Acid Dehydrogenases, 1 mg each 17 items * 1mg / item |
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme and coenzyme regeneration system (e.g. glucose and glucose dehydrogenase).
➢ D-AADH should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.
Example 1(Reduction α Ketoacids to corresponding D-amino acids)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Akita H, Hayashi J, Sakuraba H, et al. Frontiers in Microbiology, 2018, 9: 1760.
