SyncoZymes

products

Factory Free sample Nicotinamide Riboside David Sinclair - Transaminase (ATA) – SyncoZymes

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

The incredibly abundant projects administration experiences and 1 to one provider model make the superior importance of small business communication and our easy understanding of your expectations for Magnesio Dimalato 350mg Nadh 10mg , Nmn Supplement Double Wood , Best Nmn Supplement Brand , We welcome new and old customers from all walks of life to contact us for future business relationships and mutual success.
Factory Free sample Nicotinamide Riboside David Sinclair - Transaminase (ATA) – SyncoZymes Detail:

Enzymes: Are macromolecular biological catalysts, most enzymes are proteins.

Transaminases: A class of enzymes that catalyze amino transferring between amino acids and keto acids. Transaminases are key biological enzymes in asymmetric synthesis and racemic resolution of chiral amines.
Aminotransferase can be divided into four classes according to sequence and structure: Ⅰ, Ⅱ, Ⅲ and Ⅳ. ω-aminotransferases belong to class II transaminases, commonly be used in the preparation of chiral amines and unnatural amino acids, such as β-amino acids.

ω-aminotransferases: In most cases, ω-transaminase refers to a class of enzymes, that catalytic ammonia transfer reactions without α-amino acid as substrate or product.

Catalytic mechanism:

Transaminase ATA1

Enzymes Product Code Product Code
Enzyme Powder ES-ATA-101~ ES-ATA-165 a set of 65 ω-Transaminases, 50 mg each 65 items * 50mg / item, or other quantity
Screening Kit (SynKit) ES-ATA-6500 a set of 65 ω-Transaminases, 1 mg each 65 items * 1mg / item

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion efficiency.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Enzyme screening should be carried out for specific substrates because of the substrate specificity, and get an enzyme that catalyzes the target substrate with best catalytic effect.
➢ Never contact with extreme conditions such as: high temperature, high/low pH and organic solvent with high concentration.
➢ Normally, the reaction system should include substrate, buffer solution, amino donor (such as amino acids and 1-phenyl ethylamine) or receptor (such as keto acids), coenzyme (PLP), cosolvent (such as DMSO).
➢ ATA should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.
➢ All kinds of ATA have various optimum reaction conditions, so each of them should be further studied individually.

Example 1(synthesis of Sitagliptin, asymmetric synthesis) (1):

Transaminase ATA2

Example 2 (Mexiletine, Combination of kinetic resolution with asymmetric synthesis)(2):

Transaminase ATA3

1 Savile CK, Janey JM, Mundorff EC, et al. Science, 2010, 329(16), 305-309.
2 Koszelewski D, Pressnitz D, Clay D, et al. Organic letters, 2009,11(21):4810-4812.


Product detail pictures:

Factory Free sample Nicotinamide Riboside David Sinclair - Transaminase (ATA)  – SyncoZymes detail pictures


Related Product Guide:

We believe in: Innovation is our soul and spirit. Quality is our life. Customer need is our God for Factory Free sample Nicotinamide Riboside David Sinclair - Transaminase (ATA) – SyncoZymes , The product will supply to all over the world, such as: Morocco, Puerto Rico, Poland, If you are for any reason unsure which product to select, do not hesitate to contact us and we will be delighted to advise and assist you. This way we will be providing you with all the knowledge needed to make the best choice. Our company strictly follows "Survive by good quality, Develop by keeping good credit. " operation policy. Welcome all the clients old and new to visit our company and talk about the business. We are looking for more and more customers to create the glorious future.
  • The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Priscilla from Turin - 2017.11.01 17:04
    Timely delivery, strict implementation of the contract provisions of the goods, encountered special circumstances, but also actively cooperate, a trustworthy company!
    5 Stars By Laura from Switzerland - 2018.12.28 15:18
    Write your message here and send it to us