Monoamine oxidase (MAO)
Short Description:
About Monoamine oxidase
ES-MAO(Monoamine oxidase): MAO catalyze the oxidative deamination of monoamines to produce hydrogen peroxide, ammonia and corresponding aldehydes. In the catalytic process, oxygen is necessary as oxidant. There are 6 kinds of MAO enzyme products (Number as ES-MAO-101～ES-MAO-106) developed by SyncoZymes, which can be used in the oxidative deamination of monoamine compounds.
Catalytic reaction type:
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail: lchen@syncozymes.com
| Enzymes | Product Code | Specification |
| Enzyme Powder | ES-MAO-101~ ES-MAO-105 | a set of 5 Monoamine Oxidase, 50 mg each 5 items * 50mg / item, or other quantity |
| Screening Kit (SynKit) | ES-MAO-500 | a set of 5 Monoamine Oxidase, 1 mg each 5 items * 1mg / item |
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions..
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme, and coenzyme regeneration system.
➢ All kinds of MAO corresponding to various optimum reaction conditions should be studied individually.
➢ High concentration Substrate or product with may inhibit ES-MAO’s activity. However, the inhibition can be relieved by batch addition of substrate.
Example 1(Biosynthesis of (1R,5S)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hex-2-ene)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1 Tao Li, Jack Liang, Alexandre Ambrogelly et al. J. Am. Chem. Soc. 2012, 134, 6467−6472.
