β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt (reduced form) (NADPH)
NADPH is a phosphorylated derivative of nicotinamide adenine dinucleotide (NAD) at the 2'-position of the ribose ring system linked to adenine and is involved in various anabolic reactions, such as the synthesis of lipids, fatty acids and nucleotides . These reactions require NADPH as a reducing agent and a hydride donor.
According to product use, it can be divided into the following grades: biotransformation grade, diagnostic reagent grade.
Biotransformation grade:It can be used for the synthesis of pharmaceutical intermediates and APIs, mainly by cooperating with catalytic enzymes. Currently, it is mainly researched at the laboratory stage.
Diagnostic reagent grade:It is used with a variety of diagnostic enzymes as the raw material of diagnostic kits.
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① Biological synthesis, green and environmental protection, in line with the current environmental protection requirements at home and abroad.
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③ Stable supply, long-term stock supply.
| Chemical Name | NADPH |
| Synonyms | β- Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt (reduced form) |
| CAS Number | 2646-71-1 |
| Molecular Weight | 769.42 |
| Molecular Formula | C21H31N7NaO17P3 |
| EINECS号: | 220-163-3 |
| Melting point | >250°C (dec.) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | 10 mM NaOH: soluble50mg/mL, clear |
| form | Powder |
| color | White to Off-white |
| Merck | 14,6348 |
| Water Stability: | Soluble in water (50 mg/ml). |
| Sensitive | Light Sensitive |
| Test Item | Specifications |
| Appearance | White to yellow powder |
| Purity (by HPLC, %area) | ≥90.0% |
| Water content (by KF) | Report for information |
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep tightly stoppered in dark below -15℃.
NADPH is a phosphorylated derivative at the 2'- position of the ribose ring system linked to adenine in nicotinamide adenine dinucleotide (NAD), which participates in many anabolic reactions, such as the synthesis of lipids, fatty acids and nucleotides. In these reactions, NADPH is needed as a reducing agent and a donor of anion.
It can be used for the synthesis of pharmaceutical intermediates and raw materials, mainly in combination with catalytic enzymes, and is currently mainly studied in laboratory.
