β-Nicotinamide Mononucleotide (NMN)
Recently, there is good news in the field of NMN - after strict review by the professional committee of the U.S. Food and Drug Administration (FDA) authoritative organization, the NMN raw materials of Shangke Biopharmaceutical (Shanghai) Co., Ltd. (hereinafter referred to as "Shangke Bio") have been approved by the United States FDA NDI approval confirms that its NMN raw material can be officially used in the production, sales and promotion of dietary supplements in the United States, and can be found on the FDA official website as a new dietary supplement raw material, number 1247.
FDA NDI is the most important certification system in the U.S. market. Obtaining this certification not only means that the safety and quality of Shangke Bio’s products are highly recognized, but also is conducive to the continuous standardized development of the NMN industry in the long run.
| Chemical Name | β-Nicotinamide Mononucleotide |
| Synonyms | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| CAS Number | 1094-61-7 |
| Molecular Weight | 334.22 |
| Molecular Formula | C11H15N2O8P |
| EINECS号: | 214-136-5 |
| Melting point | 166 °C(dec.) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Yellow |
| Merck | 13,6697 |
| BRN | 3570187 |
| Stability: | Very Hygroscopic |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Test Item | Specifications |
| Appearance | White to off-white crystalline powder |
| Sodium content | ≤1% |
| pH value (100mg/ml) | 2.0~4.0 |
| Purity | ≥99.0% |
| Water content | ≤1% |
| Heavy metals | <10ppm |
| Arsenic | <0.5ppm |
| Lead | <0.5ppm |
| Mercury | <0.1ppm |
| Cadmium | <0.5ppm |
| Solvent residue | Ethanol≤1000ppm |
| Total Aerobic Microbial Count | <750cfu/g |
| Yeast & Mold | <25cfu/g |
| Total coliform | ≤0.92MPN/g |
| E. Coli | Negative |
| Salmonella | Negative |
| Staph. Aureus | Negative |
| Assay (on anhydrous basis) | ≥99.0% |
| Sieving rate | ≥95% |
| Bulk density | Report for information |
Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Preserve in tight, light-resistant containers, for prolonged storage keep at 2~8°C or below.
Nicotinamide Mononucleotide (NMN) is an innovative version of vitamin B3 that is a 1 step precursor to NAD+ (Nicotinamide Adenine Dinucleotide). NMN is the first cellular NAD+ restorer to be proven effective to restore cells in vivo.
Nicotinamide Adenine Dinucleotide (NAD) is one of the most important and interesting molecules in the body. It is required for over 500 enzymatic reactions and plays key roles in the regulation of almost all major biological processes (Ansari and Raghava, 2010). Above all, it may allow us to lead healthier and longer lives.
Nicotinamide Adenine Dinucleotide (NAD) exists in either its oxidized form (NAD+) or reduced form (NADH), which are critical cofactors of a number of oxireductases.
SyncoZyems as the first to obtain FDA NDI NMN approved raw material production enterprise, represent FDA official accept NMN as a new kind of material can begin to be accepted and approved for the dietary supplement ingredients in the United States.
