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OEM manufacturer Best Nicotinamide Mononucleotide Supplement - Esterase&Lipase (PLE&CALB) – SyncoZymes

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OEM manufacturer Best Nicotinamide Mononucleotide Supplement - Esterase&Lipase (PLE&CALB) – SyncoZymes Detail:

There are 26 kinds of PLE enzyme products (Number as ES-PLE-101~ES-PLE-126) developed by SyncoZymes. ES-PLE can be used for the hydrolysis of aliphatic and ester compounds, or regioselective and stereoselective resolution to synthesize chiral acids and their derivatives.

Catalytic reaction type:

Esterase&Lipase (PLE&CALB)
Esterase&Lipase (PLE&CALB)1

★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.

➢ Normally, the reaction system should include substrate, buffer solution and the ES-PLE. The esterification of some ES-PLEs is carried out in the organic phase.
➢ All kinds of ES-PLEs corresponding to various optimum reaction conditions should be studied individually.

Example 1(Biosynthesis of Pregabalin Intermediate) (1):

calb1

Example 2 (2):

calb2

Example 3 (3):

calb3

Example 4(4):

calb5

Keep 2 years below -20℃.

Never contact with extreme conditions such as: high temperature, high/low pH.

1. Xu FX, Chen SY, Xu G, e tal. Appl. Biotechnol Bioproc E, 1988, 54(4): 1030.
2. Huang, F.C., Lee, L. F., Mittal, R. S. D. e tal. J. Am. Chem.Soc, 1975, 97, 4144.
3. Kielbasinski, P., Goralczyk, P., Mikolajczyk, M., e tal. Synlett, 1994, 127.
4. Gais, H. J., Griebel, C., Buschmann, H. Tetrahedron:Asymmetry 2000, 11, 917


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OEM manufacturer Best Nicotinamide Mononucleotide Supplement - Esterase&Lipase (PLE&CALB)  – SyncoZymes detail pictures

OEM manufacturer Best Nicotinamide Mononucleotide Supplement - Esterase&Lipase (PLE&CALB)  – SyncoZymes detail pictures


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Our personnel are always inside the spirit of "continuous improvement and excellence", and together with the outstanding excellent goods, favorable price and good after-sales services, we try to gain every customer's trust for OEM manufacturer Best Nicotinamide Mononucleotide Supplement - Esterase&Lipase (PLE&CALB) – SyncoZymes , The product will supply to all over the world, such as: Lisbon, Botswana, Belgium, we rely on own advantages to build a mutual-benefit commerce mechanism with our cooperative partners. As a result, we have gained a global sales network reaching the Middle East, Turkey, Malaysia and Vietnamese.
  • Timely delivery, strict implementation of the contract provisions of the goods, encountered special circumstances, but also actively cooperate, a trustworthy company!
    5 Stars By Genevieve from Belgium - 2018.09.21 11:01
    The sales manager has a good English level and skilled professional knowledge, we have a good communication. He is a warm and cheerful man, we have a pleasant cooperation and we became very good friends in private.
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