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Phosphokinase (PKase)
About Phosphokinase
ES-PKase (Phosphokinase): catalyzes the transfer of phosphate groups on ATP to other compounds. It also catalyzes the transfer of phosphate groups on other nucleosides of triphosphate sometimes. Most kinases need divalent metal ions to participate in the reaction (generally Mg2+). There are 21 kinds of PKase enzyme products (Number as ES-PKase101~ ES-PKase-121) developed by SyncoZymes.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Cyclooxygenase (COX)
About Cyclooxygenase
ES-COX (Cyclooxygenase): catalyzes the conversion of C=C bonds to epoxide. There are 11 kinds of COX enzyme products (Number as ES-COX101~ ES-COX-111) developed by SyncoZymes. According to different catalytic mechanism, the COX of SyncoZymes is divided into haloperoxidase and styrene monooxygenase. ES-COX101, 102, 107-111 belong to haloperoxidase, while ES-COX103-106 belong to styrene monooxygenase.
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E-Mail: lchen@syncozymes.com
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Cyclohexanone monooxygenase (CHMO)
About Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): a Baeyer Villiger monooxygenase (BVMO) with cyclohexanone as the substrate, can oxidize cyclohexanone to cyclohexanol using oxygen.
It is a kind of flavin dependent enzyme. The oxidized flavin is reduced to flavin through the cycle of reducing coenzyme II (NADPH) for the next oxidation. Therefore, cofactor NADPH is necessary in flavin cycle. There is only 1 kind of CHMO enzyme product (Number as ES-CHMO101) developed by SyncoZymes, which can be used to oxidize cyclohexanone to cyclohexanone.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Carboxylic acid reductase (CAR)
About Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): catalyzes the reduction of carboxyl group to aldehyde group. In the catalytic process, ATP activation and coenzyme NADPH are required as hydrogen transporters. There are 2 kinds of CAR enzyme products (Number as ES-CAR101~ ES-CAR-102) developed by SyncoZymes.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
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Eluxadoline Intermediate methyl 5-(((S)-2-((tert-butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoate
Catalog No. SZ-2078
CAS: 1137026-67-5
Purity: 99%
Usage Eluxadoline
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E-Mail: lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate
Catalog No. SZ-2077
CAS: 1391712-57-4
Purity: 99%
Usage Eluxadoline
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E-Mail: lchen@syncozymes.com
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Adapalene Intermediate 1-(5-bromo-2-methoxy-phenyl)adamantane
Catalog No. SZ-1559
CAS: 104224-63-7
Purity: 99%
Usage Adpalene
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E-Mail: lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate oxalic acid
Catalog No. SZ-2077
CAS: 2046303-09-5
Purity: 99%
Usage Eluxadoline
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E-Mail: lchen@syncozymes.com
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Ibrutinib Intermediate (S)-1-Boc-3-hydroxypiperidine
Catalog No. SZ-1527
CAS: 143900-44-1
Purity: 99%
Usage Ibrutinib
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail: lchen@syncozymes.com
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![Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine](https://cdn.globalso.com/syncozymesnad/3-4-phenoxyphenyl-1H-pyrazolo34-dpyrimidin-4-amine.jpg)
Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Catalog No. SZ-2028
CAS: 330786-24-8
Purity: 99%
Usage Ibrutinib
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail: lchen@syncozymes.com
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Ibrutinib Intermediate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Catalog No. SZ-2028-4
CAS: 330792-70-6
Purity: 99%
Usage 25kg/barrel
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E-Mail: lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
About Phenylalanine dehydrogenase
ES-PDH: A class of oxidoreductase. The positive reaction can catalyze the oxidative deamination of L phenylalanine salt in the presence of NAD to produce phenylpyruvate salt, and the reverse reaction can catalyze the synthesis of corresponding amino acid salt from phenylpyruvate salt. Syncozymes developed 8 items of phenylalanine dehydrogenase (numbered ES-PDH-101~ES-PDH-108). ES-PDH can be used to prepare phenylalanine salt or corresponding amino acid salt from phenylpyruvic acid salt or derivatives.
Catalytic reaction type:
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E-Mail: lchen@syncozymes.com
