Threonine deaminase (TDA)
Short Description:
About Threonine deaminase
ES-TDA (Threonine deaminase): a pyridoxal phosphate protein that catalyzes the deamination of threonine to produce 2-ketobutyric acid and ammonia. Pyridoxal 5-phosphate is necessary as coenzyme in the catalytic system. There is only 1 kind of TDA enzyme product (Number as ES-TDA) developed by SyncoZymes, which can be used to prepare 2-ketobutyric acid or its derivatives from threonine.
Catalytic reaction type:
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| Enzymes | Product Code | Specification |
| Enzyme Powder | ES-TDA-101 | a set of 1 Nitrile Reductase, 50 mg each 1 items * 50mg / item, or other quantity |
★ High substrate specificity.
★ Strong chiral selectivity.
★ High conversion.
★ Less by-products.
★ Mild reaction conditions.
★ Environmentally friendly.
➢ Normally, the reaction system should include substrate, buffer solution, enzyme, coenzyme.
➢ TDA should be added last into reaction system, after the pH and temperature been adjusted to the reaction condition.
Example 1(Synthesis of L-2-aminobutyric acid from threonine)(1):
Keep 2 years below -20℃.
Never contact with extreme conditions such as: high temperature, high/low pH and high concentration organic solvent.
1. Wang, Ying, et al. Biotechnology letters, 2018, 40, 1551-1559.
